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No insurance? Every route, priced.
How much does a GLP-1 cost without insurance? Every route, priced
Medically reviewed by the NexLife clinical team, led by Adam Kennah, MD · Updated
Without insurance, brand-name
$139/mo on 12 months, every dosePrice Match Guarantee†
- Pills: the Wegovy pill or Foundayo, $149 to $299 a month
- Weekly shots: Wegovy $349 ($399 for HD); Zepbound $299 to $449 with on-time refills
- Medicare Part D: $50 through the Bridge, if you qualify
$139/mo on a 12-month plan, all-inclusive, same price at every dose
Or $169/mo month to month
Brand-name
About 3 minutes of health questions · No insurance needed · Not prescribed? No charge for medication
See all 4 plans and what a year costs
| Plan | Per month | 12 months at this rate |
|---|---|---|
| 12-month Lowest monthly price | $139 | $1,668 |
| 6-month | $149 | $1,788 |
| 3-month | $159 | $1,908 |
| Month to month | $169 | $2,028 |
Month to month costs $360 more over 12 months than the 12-month plan. Plans renew until you cancel. Longer plans bill the way you choose at checkout.
Price Match Guarantee†. Paying less elsewhere? We match your regular monthly price. How it works
4.8 out of 5 on Trustpilot, 403 reviewsLegitScript-certified
Compounded, not FDA-approved. A licensed provider prescribes it only when it offers a significant difference for you. The vial shown is an illustration.
- Licensed U.S. providers
- LegitScript certified
- Free expedited shipping
- HSA, FSA, Affirm, Klarna, Afterpay
- 24/7 support, real people
- Filled by Absolute Pharmacy (Lutz, FL) or Boudreaux’s New Drug Store (Lake Charles, LA)
Compounded tirzepatide and semaglutide aren’t FDA-approved or generics. A licensed provider prescribes them only when they offer a significant difference for you.
- Tell us about you About 3 minutes of health questions
- A licensed provider decides You’re prescribed only if it’s right for you
- Your partner pharmacy ships Usually within 1 to 2 business days, free
Key takeaways
- Brand-name, self-pay: the Wegovy pill and Foundayo are $149 to $299 a month, Wegovy pens $349 to $399, Zepbound $299 to $449 with on-time refills, Ozempic $349 to $499 and Mounjaro $499 for type 2 diabetes (checked October 25, 2026).
- Compounded, all in: semaglutide is $119 to $299 a month (median $199, 17 programs) and tirzepatide $139 to $399 (median $237, 14 programs) in our price index, checked October 13–18, 2026. Neither is FDA-approved.
- TrumpRx lists the makers’ own prices, as a coupon or a link to the maker. With Medicare Part D, the
GLP-1 Bridge charges $50 a month for Wegovy, Foundayo or the Zepbound KwikPen if you qualify. - Three offers end December 31, 2026: the $199 price for a new patient’s first two Wegovy or Ozempic pen fills, Foundayo’s reduced 2.5 and 5.5 mg prices, and Lilly’s savings cards.
- At NexLife, compounded tirzepatide is $139 a month on the 12-month plan or $169 month to month, and semaglutide $119 or $139, the same at every dose. HSA, FSA, Affirm, Klarna and Afterpay all work at checkout.
At a glance
Every GLP-1 without insurance, at a glance
Prices are what you’d pay yourself for the medication. Every option is FDA-approved except the compounded ones.
| Medicine | Maker, and how you take it | FDA-approved for | Self-pay, a month | A year at that price | Medicare, 2026–2027 |
|---|---|---|---|---|---|
| Wegovy pillsemaglutide | Novo Nordisk; a daily pill on an empty stomach | Weight loss, and lowering heart risk with heart disease, in adults | $149 (1.5 mg), $199 (4 mg), $299 (9 or 25 mg) at NovoCare | $3,588 at $299 (12 bottles) | Bridge: $50 if you qualify |
| Foundayoorforglipron | Eli Lilly; a daily pill, any time, with or without food | Weight loss in adults | $149 (0.8 or 2.5 mg), $199 (5.5 mg), $299 (9 to 17.2 mg) at LillyDirect | $3,588 at $299 (12 months) | Bridge: $50 if you qualify |
| Wegovy pensemaglutide | Novo Nordisk; a weekly pen | Weight loss (adults, and children 12 and up), lowering heart risk with heart disease, and MASH in adults | $349; $399 for Wegovy HD 7.2 mg; $199 for a new patient’s first two fills through December 31, 2026 | $4,537 (13 fills) | Bridge: $50 if you qualify |
| Zepboundtirzepatide | Eli Lilly; a weekly shot, vial or KwikPen | Weight loss; moderate to severe sleep apnea with obesity | $299 (2.5 mg), $399 (5 mg), $449 (7.5 to 15 mg) at LillyDirect, with refills within 45 days | $5,187 at 5 mg to $5,837 from 7.5 mg, with on-time refills (13 fills) | Bridge: $50 for the KwikPen, not vials |
| Ozempic pensemaglutide | Novo Nordisk; a weekly pen | Type 2 diabetes, and lowering heart and kidney risks in type 2 diabetes. Not weight loss: that use is off-label | $349 (0.25 to 1 mg), $499 (2 mg) at NovoCare; $199 for a new patient’s first two fills through December 31, 2026 | $4,537, or $6,487 at 2 mg (13 fills) | Not on the Bridge; Part D may cover it for diabetes |
| Mounjarotirzepatide | Eli Lilly; a weekly pen | Type 2 diabetes, ages 10 and up, and lowering heart risk in adults with type 2 diabetes at high risk. Not weight loss: that use is off-label | $499 at LillyDirect, every dose | — | Not on the Bridge; Part D may cover it for diabetes |
| Compounded semaglutidenot FDA-approved | A state-licensed pharmacy, for one patient; usually a weekly shot | Not FDA-approved | $119 to $299 online (median $199, 17 programs). At NexLife: $119 on 12 months, $139 month to month | At NexLife: $1,428 or $1,668 | Not on the Bridge |
| Compounded tirzepatidenot FDA-approved | A state-licensed pharmacy, for one patient; usually a weekly shot | Not FDA-approved | $139 to $399 online (median $237, 14 programs). At NexLife: $139 on 12 months, $169 month to month | At NexLife: $1,668 or $2,028 | Not on the Bridge |
Swipe the table sideways to see every column.
Self-pay prices from LillyDirect, NovoCare and wegovy.com, checked October 25, 2026, for the medication alone. A pen, KwikPen or vial fill covers 28 days, so a year is 13 fills; a pill month is 30 days. Compounded prices are all in, month to month, from our
One medicine at a time: tirzepatide without insurance and semaglutide without insurance go deeper on each.
The NexLife Price Match Guarantee†
Keep your price.
Upgrade your care.
Already on compounded tirzepatide or semaglutide? Pay less with another licensed U.S. telehealth provider or clinic, and we match your regular monthly price for as long as your plan stays active.† Plus a provider who follows your dose, a nutrition plan, a coaching call and real people 24/7.
- 1Send a receipt from the last 60 days
- 2A NexLife provider reviews your prescription
- 3Pay your matched price, at every dose
Locked while your plan is activeSame price at every doseNo membership fee
†Terms: see the Price Match Guarantee† details below. Compounded medications aren’t FDA-approved; a provider prescribes one only when it offers a significant difference for you.
Fair questions
- Will my price go up with my dose?
- No. You pay the same at every dose.
- What if I’m not prescribed?
- You aren’t charged for medication.
- Can I cancel?
- Yes, by email or phone, with 30 days’ notice. Plans renew until you cancel; our cancellation policy has the details.
- Do I need insurance?
- No. Pay with an HSA or FSA card, or with Affirm, Klarna or Afterpay at checkout.
Which fits you
Which way to pay for a GLP-1 fits you?
Start with what matters most to you. Your provider decides which medicine and dose are right for you.
If the lowest FDA-approved price matters most
Start with a pill: the Wegovy pill or Foundayo is $149 a month at the lowest doses. Both rise to $299 a month at the top doses.
If you want a weekly shot
Wegovy pens are $349 a month ($199 for a new patient’s first two fills through December 31, 2026). Zepbound is $299 to $449 at LillyDirect, by dose, with on-time refills.
If you have type 2 diabetes
Ozempic and Mounjaro are approved for type 2 diabetes, not weight loss (using them for weight loss is off-label). Self-pay, Ozempic is $349 to $499 and Mounjaro $499; a plan may cover either for diabetes. NexLife’s providers prescribe compounded tirzepatide and semaglutide for weight loss. They aren’t a treatment for type 2 diabetes and don’t replace Ozempic, Mounjaro or your diabetes care.
If you have Medicare Part D
Check the
GLP-1 Bridge first: $50 a month if you meet its BMI and health criteria. What you pay yourself outside Medicare doesn’t count toward your Part D costs.If you want one price as your dose rises
Zepbound and both pills cost more as the dose rises: Zepbound from $299 to $449 and the pills from $149 to $299, with on-time refills. Some compounded programs charge one price at every dose; at NexLife, tirzepatide is $139 a month on the 12-month plan or $169 month to month, and semaglutide $119 or $139. Neither is FDA-approved.
If your coverage ends January 1, 2027
Price your self-pay route before December 31, 2026, when several starter offers and Lilly’s savings cards end. What to do first: insurance dropped your
GLP-1?
Cheapest
What is the cheapest GLP-1 without insurance?
At the lowest doses, the cheapest FDA-approved
- $149 the lowest brand-name self-pay price Wegovy pill 1.5 mg; Foundayo 0.8 mg (or 2.5 mg through December 31, 2026)
- $119 the lowest month-to-month compounded price in our index PreventiveMD’s semaglutide, checked October 13, 2026
- $50 Medicare’s Bridge copay with Part D, if you qualify
The cheapest start isn’t the cheapest year. The Wegovy pill goes from $149 at 1.5 mg to $199 at 4 mg and $299 at 9 or 25 mg. Foundayo’s 2.5 and 5.5 mg prices are reduced only through December 31, 2026; TrumpRx.gov lists their regular prices as $199 and $299.
Compounded, the lowest in our index month to month are PreventiveMD’s $119 for semaglutide (checked October 13, 2026) and $139 for tirzepatide (checked October 15, 2026). Prepaid 12-month plans go lower per month, such as Ondra Health’s $96 for semaglutide ($1,149 upfront) and Cora’s $135 for tirzepatide ($1,620 upfront), both checked October 15, 2026.
At NexLife, compounded semaglutide is $119 a month on the 12-month plan or $139 month to month, and tirzepatide $139 or $169, at every dose. Month to month, that’s $60 and $68 under the index medians. Paying a lower regular monthly price elsewhere? Our Price Match Guarantee† matches it; prepaid rates aren’t matched.
Brand-name, self-pay
What do brand-name GLP-1s cost if you pay yourself?
Each maker sells directly at a self-pay price, for the medication alone: $149 to $499 a month by medicine and dose with on-time refills, or up to $699 for a late Zepbound refill. A prescriber’s visit is separate.
| Medicine and dose | Where | A month | A year at that price |
|---|---|---|---|
| Wegovy pill, 1.5 mg30 tablets | NovoCare | $149 a 30-day starting step | — |
| Wegovy pill, 4 mg | NovoCare | $199 a 30-day step | — |
| Wegovy pill, 9 or 25 mg | NovoCare | $299 | $3,588 (12 bottles) |
| Foundayo, 0.8 or 2.5 mga 30-day month | LillyDirect | $149 starting steps of at least 30 days each; 2.5 mg reduced through December 31, 2026 | — |
| Foundayo, 5.5 mg | LillyDirect | $199 reduced price ends December 31, 2026 | — |
| Foundayo, 9 to 17.2 mg | LillyDirect | $299 14.5 and 17.2 mg: refill within 45 days | $3,588 |
| Wegovy pen, 0.25 to 2.4 mg4 pens, 28 days | NovoCare | $349 $199 for a new patient’s first two fills (0.25 or 0.5 mg) through December 31, 2026 | $4,537 (13 fills) |
| Wegovy HD, 7.2 mg | NovoCare | $399 | $5,187 |
| Ozempic pen, 0.25 to 1 mg1 pen, 28 days | NovoCare | $349 $199 for a new patient’s first two fills (0.25 or 0.5 mg) through December 31, 2026 | $4,537 |
| Ozempic pen, 2 mg | NovoCare | $499 | $6,487 |
| Zepbound, 2.5 mgvial or KwikPen, 28 days | LillyDirect | $299 a starting dose | — |
| Zepbound, 5 mg | LillyDirect | $399 | $5,187 |
| Zepbound, 7.5 to 15 mg | LillyDirect | $449 late refills: $499 to $699 | $5,837 with on-time refills |
| Mounjaro, every dosefor type 2 diabetes | LillyDirect | $499 | — |
Swipe the table sideways to see every column.
From LillyDirect, NovoCare’s self-pay terms and wegovy.com, checked October 25, 2026. A pen, KwikPen or vial fill covers 28 days, so a year is 13 fills; a pill month is 30 days. Needles for Zepbound vials and KwikPens are extra.
Ozempic for weight loss? Ozempic is approved for type 2 diabetes, including lowering heart and kidney risks in type 2 diabetes, not for weight loss, so prescribing it for weight loss is off-label. NovoCare’s self-pay offer is only for Wegovy or Ozempic prescribed “for an FDA-approved indication within that product’s labeling.” For weight loss, Novo’s semaglutide is Wegovy. NovoCare also lists Ozempic tablets at $149 to $299 a month, by dose.
Insured but paying cash? NovoCare’s and TrumpRx’s terms say you won’t seek reimbursement from your plan or count the cost toward your deductible or out-of-pocket limit, and Lilly’s KwikPen self-pay card asks the same.
TrumpRx
Is TrumpRx cheaper for a GLP-1 without insurance?
No. TrumpRx.gov lists each maker’s own self-pay price, then sends you to the maker or gives you a coupon to show at a pharmacy.
| On TrumpRx.gov | Listed price | How you buy |
|---|---|---|
| Zepbound vialsEli Lilly | Starting at $299 | Lilly handles the order through LillyDirect |
| FoundayoEli Lilly | LillyDirect’s prices; 2.5 and 5.5 mg reduced through December 31, 2026, regular prices $199 and $299 | Through LillyDirect, with delivery or a transfer to a retail pharmacy |
| Wegovy penNovo Nordisk | $199 for a new patient’s first two fills (through December 31, 2026), then $349; $399 for HD 7.2 mg | A coupon you show at a pharmacy |
| Wegovy pillNovo Nordisk | Starting at $149 | A coupon you show at a pharmacy |
| Ozempic penNovo Nordisk | $199 for a new patient’s first two fills (through December 31, 2026), then $349; $499 at 2 mg | A coupon you show at a pharmacy |
Swipe the table sideways to see every column.
TrumpRx.gov listings, checked October 25, 2026. Every price is self-pay.
With Medicare: “You can’t buy drugs directly from TrumpRx,” Medicare.gov says, and what you pay through it doesn’t count toward your Medicare deductible or out-of-pocket maximum.
How these prices got here, dated: will tirzepatide get cheaper?
Medicare
Is there a cheaper way to get a GLP-1 if you have Medicare?
Yes, if you qualify: through Medicare’s
| Who | Adults 18 and up with Medicare drug coverage (Part D) |
|---|---|
| BMI and health | When you start |
| Covered | Wegovy (pen or pill), Foundayo and the Zepbound KwikPen. Not Zepbound vials or single-dose pens, and not compounded medicines |
| What you pay | $50 for a one-month supply (28 or 30 days, by drug). It doesn’t count toward your Part D deductible or out-of-pocket limit |
| How | Your prescriber sends the prescription and a prior authorization, certifying you’re in a diet-and-exercise lifestyle program. Approval lasts through December 31, 2027 |
| Not eligible | People whose Part D plan already covers their |
Paying yourself instead? NovoCare’s self-pay terms include people with government coverage who choose to pay themselves, and NexLife accepts self-pay members with Medicare. Self-pay purchases don’t count toward your Part D deductible or out-of-pocket limit, and NexLife’s Price Match Guarantee† isn’t open to people with Medicare. Step by step: Medicare and
Compounded
What does compounded semaglutide or tirzepatide cost without insurance?
$119 to $299 a month for semaglutide and $139 to $399 for tirzepatide, all in, month to month, across the 21 online programs in our price index (checked October 13–18, 2026). Neither is FDA-approved.
- $199 median month-to-month price for compounded semaglutide 17 programs
- $237 median for compounded tirzepatide 14 programs
- 10 of 17 semaglutide programs say their price is the same at every dose for tirzepatide, 9 of 14
“All in” matters. Four programs in our index add a $75 to $99 monthly membership to the medication, and some charge $50 to $150 more in month two than in month one. The prices above include every required fee.
What it is, and isn’t. A state-licensed pharmacy prepares compounded semaglutide or tirzepatide for one patient’s prescription. It isn’t FDA-approved, it isn’t a generic, and it isn’t Wegovy or Zepbound. The FDA’s advice: fill a prescription at a state-licensed pharmacy, and be wary of a seller that “offers medicine at deep discounts or prices that seem too good to be true.”
Paying less elsewhere? Our Price Match Guarantee† matches a lower regular monthly price from another licensed U.S. telehealth provider or clinic; prepaid rates aren’t matched.
Every program, dated: our
Step by step
How do you get a GLP-1 without insurance?
In four steps: a prescription, a pharmacy route, a way to pay, and refills on time.
Get a prescription
From your own doctor or a licensed telehealth provider. The makers’ self-pay prices cover the medication only, so the prescriber’s visit is a separate cost unless a program includes it.
Pick the pharmacy route
LillyDirect for Zepbound, Mounjaro or Foundayo; NovoCare Pharmacy for Wegovy or Ozempic; a TrumpRx coupon at a pharmacy for Wegovy or Ozempic; or a telehealth program that includes the medication.
Choose how to pay
A card, an HSA or FSA card where your plan allows it, or a pay-later plan where it’s offered. Lilly lists Zepbound, Mounjaro and Foundayo as HSA/FSA eligible, noting that eligibility may vary by plan.
Refill on time
Zepbound’s $449 price from 7.5 mg, and Foundayo’s $299 at 14.5 or 17.2 mg, need a refill within 45 days. Late, Zepbound costs $499 to $699.
Ways to pay
Can you use an HSA, FSA or pay-later plan for a GLP-1?
Often, yes. Lilly lists Zepbound, Mounjaro and Foundayo as HSA/FSA eligible, though eligibility may vary by plan, and NexLife takes HSA, FSA, Affirm, Klarna and Afterpay.
HSA or FSA. Your plan’s rules decide what it reimburses. At NexLife, HSA and FSA cards work at checkout, and NexLife provides a letter of medical necessity if your plan asks for one. The IRS rules and this year’s limits: HSA and FSA for tirzepatide.
Pay later. At NexLife, Affirm, Klarna and Afterpay are offered at checkout. The lender decides approval and shows your payments, and any interest, before you confirm. What each payment comes to: tirzepatide with Affirm, Klarna or Afterpay.
What’s changing
Will GLP-1 prices without insurance change in 2027?
Several offers end on December 31, 2026, and Medicare’s prices change on January 1, 2027. Here’s each dated change, with its source.
The $199 price for a new patient’s first two Wegovy or Ozempic pen fills ends. At NovoCare, the prescription must be written and received by then, and ship by January 31, 2027.
Foundayo’s reduced 2.5 and 5.5 mg prices end; TrumpRx.gov lists their regular prices as $199 and $299.
Lilly’s Zepbound savings cards end, including its KwikPen self-pay card. LillyDirect’s self-pay prices list no end date.
Medicare’s negotiated price for semaglutide (Ozempic, Rybelsus and Wegovy) starts: $274 for a 30-day supply, against a 2024 list price of $959. That’s what Medicare pays for covered uses, not your copay.
Novo Nordisk’s list price for Wegovy and Ozempic falls to $675; Novo says its self-pay prices don’t change.
Medicare’s
GLP-1 Bridge is set to end.
Safety
What should you know about GLP-1 safety before you buy?
Paying yourself doesn’t change a medicine’s risks: get it prescribed, and follow your provider’s plan. These facts are from the Zepbound (August 2026) and Wegovy (June 2026) labels.
- Both carry a boxed warning about thyroid C-cell tumors, seen in rodents; whether they happen in people isn’t known. Neither should be used with a personal or family history of medullary thyroid carcinoma (MTC), or with MEN 2.
- The most common side effects are digestive: nausea, diarrhea, vomiting, constipation and stomach pain. Both labels also list tiredness, burping, reflux and hair loss; Wegovy’s adds headache and dizziness.
- Serious risks on both labels: pancreatitis, gallbladder disease, kidney injury from dehydration, severe stomach problems, serious allergic reactions, low blood sugar with insulin or a sulfonylurea, and food entering the lungs under anesthesia. Wegovy’s also lists a faster heart rate.
- Pregnancy and birth control: stop Zepbound when a pregnancy is recognized, and stop Wegovy at least 2 months before a planned pregnancy. On Zepbound, birth control pills may work less well for 4 weeks after starting and after each dose increase, so its label advises a non-oral or added barrier method.
- One
GLP-1 at a time: Zepbound’s label doesn’t recommend using it with anotherGLP-1 medicine.
Foundayo, Mounjaro and Ozempic each have their own label, and your prescriber reviews the one for your medicine. Questions about a side effect? Call or text us 24/7 at
At NexLife
What does a GLP-1 cost at NexLife without insurance?
One monthly price at every dose, with no membership fee and no insurance needed. A licensed provider decides if treatment is right for you.
| Plan | Compounded tirzepatide | Compounded semaglutide |
|---|---|---|
| 12-month plan | $139 a month | $119 a month |
| 6-month plan | $149 a month | $125 a month |
| 3-month plan | $159 a month | $132 a month |
| Month to month | $169 a month | $139 a month |
| A year on the 12-month plan | $1,668 | $1,428 |
Swipe the table sideways to see every column.
NexLife’s prices, the same at every dose, with no membership fee. Compounded medicines aren’t FDA-approved or generics.
Your provider
A licensed provider reviews your health history online, or by secure video where your state requires a live visit, and prescribes only if it’s right for you.
Your pharmacy
Absolute Pharmacy (Lutz, FL) or Boudreaux’s New Drug Store (Lake Charles, LA), both state-licensed 503A pharmacies.
Your shipment
Free expedited shipping, usually within 1 to 2 business days of your prescription.
Your care
A nutrition plan, a 1:1 coaching call and a provider who follows your dose.
Your payment
Card, HSA or FSA (with a letter of medical necessity if your plan asks), or Affirm, Klarna or Afterpay.
Your questions
Real people answer 24/7 at
(949) 818-8000 , by call or text.
Paying less for compounded medication elsewhere? Our Price Match Guarantee† matches a lower regular monthly price from another licensed U.S. telehealth provider or clinic, with a receipt from the last 60 days.
The people behind it. Adam Kennah, MD, board-certified in emergency medicine (American Board of Emergency Medicine), is NexLife’s medical director. NexLife is LegitScript-certified and rated 4.8 out of 5 on Trustpilot from 403 reviews (read October 21, 2026). Not prescribed? You aren’t charged for medication.
Two medications.
One flat price at every dose.
No membership fee. Provider care, a nutrition plan, coaching and shipping are included. Paying less with another licensed provider? We match your regular monthly price.†
12-month plan $139/mo
Tirzepatide
Weekly and dual-action. Care, coaching and shipping included. On a 12-month plan; $169/mo month to month.
Check my eligibilityCompounded, not FDA-approved · Not prescribed? No charge for medication
12-month plan $119/mo
Semaglutide
Weekly
Compounded, not FDA-approved · Not prescribed? No charge for medication
- Tell us about you About 3 minutes of health questions
- A licensed provider decides You’re prescribed only if it’s right for you
- Your partner pharmacy ships Usually within 1 to 2 business days, free
Compounded, not FDA-approved. A licensed provider prescribes it only when it offers a significant difference for you. Vials shown are illustrations; your pharmacy’s label will look different. Every plan and price · Price Match Guarantee† terms
GLP-1 without insurance: your questions
How much does a GLP-1 cost without insurance?
Without insurance, brand-name
What is the cheapest GLP-1 without insurance?
For FDA-approved medicines, $149 a month: the Wegovy pill at 1.5 mg or Foundayo at 0.8 mg, both starting doses, rising to $299 at higher doses (checked October 25, 2026). Compounded semaglutide starts lower, at $119 month to month in our index (checked October 13, 2026), but isn’t FDA-approved. With Part D, the Bridge is $50 if you qualify.
How do you get a GLP-1 without insurance?
Get a prescription from your doctor or a licensed telehealth provider, then buy at the maker’s self-pay price (LillyDirect or NovoCare Pharmacy), with a TrumpRx coupon at a pharmacy, or through a program that includes the medication. Brand self-pay prices cover the medicine only, so the prescriber’s visit is extra.
What does a year of GLP-1 treatment cost without insurance?
At self-pay prices, $3,588 for the Wegovy pill at its 25 mg maintenance dose or for Foundayo at $299 a month; $4,537 for Wegovy pens; and $5,837 for Zepbound from 7.5 mg with on-time refills (13 four-week fills). Compounded tirzepatide at NexLife is $1,668 on the 12-month plan or $2,028 month to month; it isn’t FDA-approved.
Is TrumpRx the cheapest way to buy a GLP-1 without insurance?
No. TrumpRx.gov lists the makers’ own self-pay prices: Zepbound vials starting at $299 through LillyDirect, and Wegovy and Ozempic pens at $349 for most doses after a new patient’s first two fills at $199 (through December 31, 2026), as a pharmacy coupon (checked October 25, 2026). With Medicare, those purchases don’t count toward your deductible or out-of-pocket maximum.
Can I use HSA, FSA or pay-later plans for a GLP-1 without insurance?
Often. Lilly lists Zepbound, Mounjaro and Foundayo as HSA/FSA eligible, though eligibility may vary by plan. At NexLife, HSA and FSA cards work at checkout, with a letter of medical necessity if your plan asks, and so do Affirm, Klarna and Afterpay, which decide approval and show your payments first.
With Medicare, is the GLP-1 Bridge cheaper than paying without insurance?
If you qualify, yes: $50 a month for Wegovy, Foundayo or the Zepbound KwikPen, against $149 to $449 self-pay with on-time refills. You need Part D, a BMI of 35 or more (or lower with certain conditions) when you start, and prior authorization. NovoCare and NexLife also accept self-pay from people with Medicare.
Is compounded GLP-1 medication cheaper than brand-name without insurance?
Usually: the medians in our index are $199 a month for compounded semaglutide and $237 for tirzepatide (checked October 13–18, 2026), against $349 for a Wegovy pen and $449 for Zepbound from 7.5 mg with on-time refills. But it’s a different product: compounded medication isn’t FDA-approved, isn’t a generic, and wasn’t studied in the brands’ trials.
Can I get Ozempic for weight loss without insurance?
Not through Novo’s self-pay program: NovoCare sells Ozempic only when it’s prescribed for an FDA-approved use, and Ozempic is approved for type 2 diabetes, not weight loss, so prescribing it for weight loss is off-label. Novo’s semaglutide for weight loss is Wegovy, at $349 a month self-pay, or $149 to $299 for the Wegovy pill (checked October 25, 2026).
Will GLP-1 prices without insurance change in 2027?
Several offers end first: on December 31, 2026, the $199 price for a new patient’s first two Wegovy or Ozempic pen fills, Foundayo’s reduced 2.5 and 5.5 mg prices and Lilly’s savings cards all end. On January 1, 2027, Novo’s list price falls to $675, which Novo says doesn’t change its self-pay prices.
Important safety information
Compounded tirzepatide and semaglutide are not FDA-approved, and the FDA hasn’t reviewed them for safety, effectiveness or quality. A provider prescribes them only when they offer a significant difference for you compared with an FDA-approved product. Both medicines may cause thyroid tumors, including cancer: don’t use either if you or a family member has had medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2).
Read the full safety information
In studies with rodents, both medicines caused thyroid tumors; it isn’t known whether they cause them in people. Tell your provider if you notice a lump or swelling in your neck, hoarseness, trouble swallowing or shortness of breath. Serious side effects can include inflammation of the pancreas (pancreatitis), gallbladder problems, low blood sugar (especially with insulin or sulfonylureas), kidney problems from dehydration, severe stomach problems, serious allergic reactions, vision changes in people with type 2 diabetes, and a faster heart rate. Tell your care team before any surgery or procedure that uses anesthesia or deep sedation. Don’t combine either medicine with other
Tirzepatide can make birth control pills less effective: switch to a non-oral method, or add a barrier method such as condoms, for 4 weeks after you start and for 4 weeks after each dose increase. Both medicines may harm an unborn baby. Semaglutide should be stopped at least 2 months before a planned pregnancy. Tell your provider right away if you’re pregnant, planning to be, or breastfeeding.
This is a summary, not the complete safety information. Read the full Prescribing Information for FDA-approved tirzepatide (Zepbound) and semaglutide (Wegovy), and talk with your provider. You can report side effects to the FDA at
† NexLife Price Match Guarantee: for new NexLife members switching from a licensed U.S. telehealth provider or clinic with an active prescription for compounded tirzepatide or semaglutide. We match your regular all-in monthly price there (medication plus any required membership, program or visit fee, on a month-to-month plan); first-month offers, coupons, referral credits and prepaid multi-month rates aren’t matched. Proof from the last 60 days required. A licensed provider must determine that treatment is right for you. Not open to people with Medicare, Medicaid or TRICARE coverage. Full terms.
About NexLife. NexLife is a telehealth and care-coordination platform. Care is delivered through affiliated, physician-owned medical groups, and licensed providers decide whether treatment is right for you. NexLife doesn’t make or compound medication: state-licensed partner pharmacies fill each prescription, and we coordinate the rest. Available only in states where our affiliated providers are licensed.
Who checked this page
Leads the NexLife clinical team, which medically reviews each of NexLife’s guides, including this one.
Makers’ prices, TrumpRx, Medicare’s rules and the labels checked October 25, 2026; compounded prices October 13–18, 2026.
- How we checked. Every brand-name price comes from the maker’s own pages, read on October 25, 2026: LillyDirect for Zepbound, Mounjaro and Foundayo, and NovoCare and wegovy.com for Wegovy and Ozempic, plus TrumpRx.gov’s listings. Medicare’s rules come from Medicare.gov and CMS, and safety facts from the Zepbound, Wegovy and Ozempic labels, read the same day. Compounded prices come from our
GLP-1 price index, checked October 15, 2026 (October 13–18, 2026 for semaglutide). A year’s total is our arithmetic: 13 four-week fills for pens, KwikPens and vials, 12 months for pills and for NexLife. We don’t forecast prices. Zepbound, Mounjaro and Foundayo are trademarks of Eli Lilly and Company; Ozempic, Wegovy and Rybelsus of Novo Nordisk. NexLife isn’t affiliated with either. - Every fact, sourced. Each price and rule links to the page it comes from.
- How we make money. NexLife is a telehealth and care-coordination platform. We earn revenue when people join NexLife.
- Corrections, fast. See something wrong or out of date? Email care@nexlife.us and we’ll fix it.
Paying less elsewhere? We match it.†
You know what each route costs. Next: a 3-minute check.
No insurance needed. A licensed provider decides if compounded tirzepatide or semaglutide is right for you: $139 or $119 a month on the 12-month plan, or $169 or $139 month to month.
4.8 out of 5 on Trustpilot · Medical director Adam Kennah, MD (NPI 1144260043) · LegitScript-certified
Compounded medications aren’t FDA-approved. A provider prescribes one only when it offers a significant difference for you.
- 1Tell us about you
Start online with your health history.
- 2A licensed provider decides
Online, or by secure video where your state requires a live visit. You’re prescribed only if treatment is right for you.
- 3We ship it, then stay with you
Our partner pharmacy usually ships within 1 to 2 business days. Free shipping, and questions come to us 24/7, never to the pharmacy.
Sources
- LillyDirect: Zepbound self-pay prices, KwikPen and vials (CMAT-05333 08/2026). Checked October 25, 2026.
- LillyDirect: Mounjaro self-pay prices. Checked October 25, 2026.
- LillyDirect: Foundayo self-pay prices. Checked October 25, 2026.
- Eli Lilly: FDA approves Foundayo (orforglipron) (April 1, 2026). Read October 25, 2026.
- Eli Lilly: Zepbound full terms and conditions (Self Pay Journey Program and savings cards). Read October 25, 2026.
- Eli Lilly: Zepbound savings card and coverage. Read October 25, 2026.
- NovoCare Pharmacy: self-pay terms and prices for Wegovy and Ozempic. Read October 25, 2026.
- Novo Nordisk: What to pay for Wegovy. Checked October 25, 2026.
- TrumpRx.gov: Zepbound vial. Checked October 25, 2026.
- TrumpRx.gov: Foundayo. Checked October 25, 2026.
- TrumpRx.gov: Wegovy pen. Checked October 25, 2026.
- TrumpRx.gov: Wegovy pill. Checked October 25, 2026.
- TrumpRx.gov: Ozempic pen. Checked October 25, 2026.
- Medicare.gov: Weight loss drugs (the Medicare
GLP-1 Bridge). Read October 25, 2026. - CMS: Medicare
GLP-1 Bridge (page modified July 13, 2026). Read October 25, 2026. - CMS: Medicare drug price negotiation, negotiated prices for 2027 (fact sheet). Read October 25, 2026.
- Novo Nordisk: US list price reduction for Wegovy, Ozempic and Rybelsus (February 24, 2026). Read October 25, 2026 for our Wegovy 2027 price guide.
- Zepbound (tirzepatide) prescribing information, Eli Lilly, revised August 2026. Read October 25, 2026.
- Wegovy (semaglutide) prescribing information, Novo Nordisk, revised June 2026. Read October 25, 2026.
- Ozempic (semaglutide) prescribing information, Novo Nordisk, revised May 2026. Read October 25, 2026.
- Foundayo (orforglipron) prescribing information, Eli Lilly, revised July 2026 (dose steps). Read October 25, 2026.
- FDA: Compounding and the FDA, questions and answers. Read October 25, 2026.
- FDA: Concerns with unapproved
GLP-1 drugs used for weight loss (updated October 1, 2026). Read October 25, 2026. - NexLife:
GLP-1 price index. Tirzepatide checked October 15, 2026; semaglutide October 13–18, 2026. - NexLife: pricing, every plan.
- NexLife on Trustpilot. 4.8 out of 5 from 403 reviews, read October 21, 2026.